Post Immunisation Myelin Oligodendrocyte Glycoprotein Antibody Associated Disease with Partial Cervical Myelopathy Managed Conservatively Through Ayurveda – A Case Report

Abstract

Myelin Oligodendrocyte Glycoprotein antibody-associated disorder (MOGAD) is a newly discovered autoimmune demyelinating condition that is frequently associated with acute disseminated encephalomyelitis. It typically develops after infection or immunisation and is characterised by severe clinical episodes such as limb paralysis, loss of sensation, impaired bowel bladder control, and blurring of vision. Intravenous methylprednisolone (IVMP) 1,000 mg once day for 5 days is the conventional therapy for a MOGAD attack, which can last for a long time and is accompanied with post-administration difficulties. Greevastambha and sarvanga roga can be correlated as ayurvedic terminologies based on the signs and symptoms of MOGAD. A 35-year-old female patient diagnosed with MOGAD and Partial Cervical Myelopathy managed conservatively through Jwarahara, Amavatahara and Vatavyadhi Chikitsa got symptomatic relief, functional and quality of life improvement with 58 days of in-patient treatment at Department of Salyatantra, Govt. Ayurveda College Tripunithura, Ernakulam, Kerala.