Role of Virechana Karma, Vidangadi Churna and lifestyle modification in Metabolic syndrome (Medoroga): A Case Study Santvana Sharma P.G. Scholar, P.G. Dept. of Kayachiktsa, National Institute of Ayurveda, Jaipur, Rajasthan, India Udai Raj Saroj Associate Professor, P.G. Dept. of Kayachiktsa, National Institute of Ayurveda, Jaipur, Rajasthan, India Ram Kishor Joshi Professor & HOD, P.G. Dept. of Kayachiktsa, National Institute of Ayurveda, Jaipur, Rajasthan, India Keywords: Atherogenic dyslipidemia, Atherosclerotic disease, Cardiovascular disease, Dhatvagnimandya, Medoroga Abstract Metabolic syndrome is a group of co-morbidities which pose as a risk factor for cardiovascular disease. It comprises of hypertension, central obesity, impaired glucose metabolism and dyslipidemia. It can be considered under broad umbrella of Santarpaka Nimittaja Vyadhi and can be managed using Chikitsa Sutra for Santarpanottha Vyadhi. In present case study, Virechana was performed to a diagnosed patient of metabolic syndrome, followed with oral medication Vidangadi Churna for 30 days (total duration 45 days). Strict dietary and lifestyle modification including regular physical activity were also suggested to the patient during this period. Patient was assessed on certain symptoms like Kshudra Shwasa, Trisha, Atinidra, etc. together with NCEP ATP III criteria, 2001 before initiation and after the treatment. Symptoms related to Medodushti relieved and also body weight (93 to 81 kg), BMI - 25.3- 24.89, FBS- 118.90 - 103.80, Triglycerides- 239.5-105.3, Total Cholesterol-217.2-191.6 mg/dl, LDL-127.3-112.7 mg/dl, VLDL- 47.9-21.1 mg/dl, HDL- 42.0- 57.8, Average blood pressure - 150/ 100 to 130/ 90 mm. of Hg decreased after treatment. Virechana and Vidangadi Churna accompanied by lifestyle modification are effective in the management of metabolic syndrome. pdf Published 2021-09-28 Issue Vol 5 No 3 (2021): July-September 2021 Section Case Reports